Research Projects

Project RISK-UPDATE will support the reintegration of Dr Talya Miron-Shatz, after four years spent as post-doctoral research collaborator with Nobel Laureate Prof. Daniel Kahneman at Princeton University, in the USA. Dr Miron-Shatz’s new host institution is Ono Academic College, Israel, which has agreed to set up a new research centre to facilitate...

'Exosomes are small vesicles which mediate cell-cell communication by transporting across the extracellular environment specific “packages” of RNA and proteins. Importantly, exosomes carry translation initiation factors (TIFs) and miRNAs, a class of short non-coding RNAs with regulatory activity on the expression of the transcriptome of a cell. In...

New knowledge is not necessarily readily applied in medicine, even when there is evidence of its effectiveness. As a result of the gap between knowing and doing, policy makers, professional care providers, patients and their families have benefited too little from new developments. Implementation research has developed models for stepwise...

Given the increasing number of patients/consumers with dementia, political action is urgently required to prepare the health care services throughout Europe to deliver cost effective high quality long-term care to people concerned. Currently there is a lack of clinical research data of patients/consumers and informal caregivers to develop best...

The ITRIBIS project is envisaged to improve research at the Institute of Biomedicine of Seville (IBiS) and to help this center to become a reference of biomedical translational research applied to prevalent diseases in Southern Europe. It also aims to boosting the transfer of results to the clinical setting and to the local biotechnological...

The main goal of the proposed project IEGLO is the development of a handheld tracking device for elderly or Alzheimer disease people. At present, in Europe approximately 4.000.000 people are Alzheimer disease-ridden. Especially this people get very often in situations where they are un-oriented. They need mentoring by either their family members or...

Neuroinflammatory disease, in particular multiple sclerosis affects more than 700.000 people within Europe alone. European countries are at the forefront of neuroimmunological research and students in medicine and biology are greatly attracted by the field. Neuroimmunology research further impacts our understanding of the ethiopathology of other...

In DynICP, we propose to develop an advanced, portable prototype of a non-invasive intracranial dynamic pressure (dynamic ICP) diagnosing and monitoring device which can be used at hospitals, point of care as well as at home. This device will consist of a wearable head gear capable of precise positioning of two ultrasonic transducers, software and...

The European costs of dementia were estimated €177 billion and there is a growing gap between burden and budget. The debilitation associated with dementia makes it the most feared of conditions related to ageing . Modelling studies have estimated that if obesity rates dropped by 5%, dementia prevalence rates would be lower by 6% and a decline in...

The eHealthMonitor project provides a platform that generates a Personal eHealth Knowledge Space (PeKS) as an aggregation of all knowledge sources (e.g., EHR and PHR) relevant for the provision of individualized personal eHealth services. This is realised by integrating service-oriented architecture, knowledge engineering, multiagent systems, and...

The current research proposes new optical spectroscopic and interferometric microscopy and nanoscopy techniques for accurate measurements and visualization of biological cell structure, organization, stiffness and dynamics by recording the cell spatial, temporal, and refractive-index structure on sub-wavelength and sub-Hertz scales. The following...

Beta-amyloid peptide, a component of senile plaques and generated by proteolytic cleavage of the amyloid precursor protein (APP), is a key factor in the pathogenesis of Alzheimer disease (AD). Beta-amyloid peptide has been shown to influence negatively some important mitochondrial activities such as reducing the efficiency of ATP-production via...