Research Projects

Late-onset Alzheimer’s disease (LOAD) is a neurodegenerative disorder that currently affects 2% of the population in industrialized countries; the risk of LOAD increases in individuals beyond the age of 70 and it is predicted that the incidence of LOAD will increase 4-fold within the next 50 years which may cause a great socioeconomic problem...

The Project eBrain-Health will deliver a distributed research platform for modeling and simulating complex neurobiological phenomena of human brain function and dysfunction in a data protection compliant environment. It will provide thousands of multilevel virtual brains from patients and healthy human controls for research and innovation. Brain...

'We aim develop in-vivo imaging biomarker of multidrug transporter function as a generic tool for the prediction, diagnosis, monitoring and prognosis of major CNS diseases, as well as to provide support and guidance for therapeutic interventions. Multidrug transporters actively transport substrates (including multiple CNS drugs) against...

Independent living of senior citizens is one of the main challenges linked to the ageing population, due to the impact on: (a) the life of the elderly people, (b) the national health systems, (c) the insurance companies, (d) the relatives and (e) the care-givers. Senior citizens may suffer from a number of diseases, including the decline in...

Follow.Me aims to satisfy people’s desire of monitoring the position of elderly people with different forms of dementia and Alzheimer, in order to prevent danger situations. Caregivers and family members will be able to track their patients and loved ones using geofencing technologies in order to know when they leave or enter a given area, the...

FreeWalker will integrate several proven components of AAL assistive devices and technologies, for a flexible and versatile solution for guiding and monitoring elderly or impaired persons in the outdoor environment and supporting caregivers by providing emergency information to recover disoriented persons safely. The primary target groups in...

Get Ready For Activity – persuasive ambiences is the modular application of ambient lighting, sound and scents research to create room ambiences for supporting people with dementia (PwD) and their caregivers in their daily activities and structure and positively influence erratic behaviour (depression and agitation) of PwD. The project aims to...

The number of elderly living with cognitive impairment is growing rapidly due to increasing life expectancy. The percentage of those who live alone depends upon the condition (i.e. roughly 30% of those diagnosed with dementia) but the majority would like to live in their own home or with family, provided that it is safe, comfortable, and cost...

Neuroinflammatory disease, in particular multiple sclerosis affects more than 700.000 people within Europe alone. European countries are at the forefront of neuroimmunological research and students in medicine and biology are greatly attracted by the field. Neuroimmunology research further impacts our understanding of the ethiopathology of other...

ProACT targets Europe’s 50 million multimorbid patients to proactively self-manage and offset the EU’s annual €700billion cost of chronic disease management. ProACT aims at providing and evaluating an open application programming interface to integrate a variety of new and existing technologies to advance ‘home based’ integrated care (IC). Cloud...

The eHealthMonitor project provides a platform that generates a Personal eHealth Knowledge Space (PeKS) as an aggregation of all knowledge sources (e.g., EHR and PHR) relevant for the provision of individualized personal eHealth services. This is realised by integrating service-oriented architecture, knowledge engineering, multiagent systems, and...

The overall aim is to further the understanding of the BBB in health and disease states towards the development of innovative brain delivery systems, especially for biopharmaceuticals (e.g., peptides, antibodies, etc.) and the identification of novel disease drug targets (Alzheimer’s Disease, MS, metabolic disease).

The related key deliverables...