On 9 October 2024, Linus Jönsson (Karolinska Institutet), project coordinator of the Innovative Health Initiative (IHI) funded PROMINENT project, presented the project’s objectives and recent work at the Alzheimer Europe Conference in Geneva, Switzerland. PROMINENT aims to support early and precise Alzheimer’s disease (AD) diagnostics, treatment eligibility, and decision-making for both people affected by neurodegeneration as well as clinicians. The presentation was part of a sponsored symposium focussed on European platforms advancing dementia detection, diagnosis and care. Linus discussed PROMINENT’s integration of advanced predictive models that are being further developed as part of the project and clinical decision-support systems, which guide clinicians in selecting tailored diagnostic pathways based on individual patient profiles. This approach aims to reduce unnecessary testing and increase diagnostic accuracy, potentially making care more personalised and efficient.
The system also includes a component for analysing treatment eligibility, helping clinicians determine which patients are most likely to benefit from new disease-modifying treatments, including emerging therapies in AD. He further underscored the importance of data integration within the platform, which aggregates data from various medical records and imaging repositories to refine diagnostic processes further. By automating data analysis, PROMINENT aims to offer a streamlined experience for healthcare providers, ultimately allowing for more timely interventions. PROMINENT also actively involves patients and caregivers, emphasising their roles in improving data quality and relevance through Public Involvement, that is conducted through Alzheimer Europe’s involvement in the project. The recording of the presentation is available here:
