On 5 March, an international team of researchers from the European Prevention of Alzheimer's Dementia (EPAD) project published an article in the journal of Alzheimer’s disease entitled “Cognitive Functions as Predictors of Alzheimer’s Disease Biomarker Status in the European Prevention of Alzheimer’s Dementia Cohort”. The study examined the relationship between the main biomarkers of Alzheimer’s disease (AD) and the cognitive performance in the first five hundred research participants recruited into the EPAD Longitudinal Cohort Study (LCS). This cohort represents a general population-based registry of volunteers at dementia risk undergoing clinical examination prior to recruitment into the EPAD clinical trials. Analysis showed that the majority of research participants had elevated biomarker levels, with significant associations between an episodic verbal memory task and tau, while amyloid-ß was associated with a central executive task.
http://dx.doi.org/10.3233/JAD-191108
The EPAD project has received support from the Innovative Medicines Initiative Joint Undertaking under grant agreement n° 115736, resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution.
