Research Projects

Joint Action on Dementia 2015-2018. The Joint Action will focus on two phases on work: approximately 12 months on developing a consensus on the best evidence of effective action in 4 key areas (diagnosis and post-diagnostic support; crisis and care coordination; quality of care in residential care settings; and dementia-friendly communities); and...

The long-term goal of this project is to understand how neuronal assemblies exchange information (functional or neuronal communication), and how variability in neuronal communication explains variability in behavioural performance, both in the intact and injured brain. Communication involves temporal interactions between neuronal assemblies either...

Dementia is a major healthcare challenge worldwide due to its high incidence and its strong impact on the life quality of patients and on society as a whole. Development of treatments for the mitigation of memory impairment in patients with dementia has proven very challenging, partly due to our limited understanding of the underlying mechanisms of...

MADIA aims at realizing a versatile and cheap diagnostic device based on magnetoresistive sensors, microfluidic device, ultra–small Magnetic Nanoparticles (MNPs) and advanced bio-chemical functionalization methods for the early and ultrasensitive. in vitro detection of biomarkers trustfully associated with 2 incurable neurodegenerative diseases...

Peptide-lipid interactions are critical in several biomedical matters that seem uncorrelated at a first glance. MEMPEPACROSS deals with some of these: 1) Lipid membrane-interactions are the key for the understanding of dengue virus assembly and can constitute a target for its inhibition. Viral hemorrhagic fever caused by dengue virus is a serious...

MEMENTO provides a solution to help people with dementia to life with a decline of memory – short term memory as well as long term memory. MEMENTO provides a tool to create own set of memories in everyday life. It’s your own picture, voice and video diary. MEMENTO addresses people with early and middle level of dementia such as those subjects with...

Advances in neuroscience have returned the focus on learning, placing the relationship between sleep and consolidation of memory at the centre of academic debate. There are two types of sleep: rapid eye movements and slow wave sleep (SWS). Although both types of sleep have been related to memory consolidation, accumulated evidence points more to...

MEMOSAD aims at defining the molecular mechanisms of Abeta- and Tau-induced synaptotoxicity and at developing disease-modifying therapeutics for the prevention of memory loss in Alzheimer disease (AD). Insoluble aggregates of the two proteins provide the pathological hallmarks of this incurable brain disorder. Early stage AD is characterized by a...

Vascular dementia and heart failure represent major health burden to morbidity, mortality and quality of life. Comorbidities (hypertension, aging, diabetes, etc.) affect all organs, but the brain and heart are especially sensitive to these chronic stresses resulting in cognitive impairment (a mental disorder) and heart failure (a non-mental...

Dementia researchers are increasingly focusing their efforts on finding ways to prevent the onset of dementia symptoms in the first place, and for this they need to work with people who are still in the very earliest stages of the disease. The MOPEAD project aims to identify and test different models for engaging with this important group and...

The prevalence of type 2 diabetes mellitus (T2D), cardiovascular disease (CVD), and dementia is rapidly increasing worldwide and is therefore a major public health concern. Carbohydrate intake (40-80%) represents the main source of energy in most populations and the quality more than the quantity has a large effect on health. Recently, a...

Multi-Sensory Environments (MSEs) is a discipline of occupational therapy that helps treat cognitive and sensory deficiencies (in memory, attention, social interaction…) of people with developmental disabilities, physical disabilities, neuro-degenerative diseases and or brain-injuries. These conditions which include autism, dementia, Down syndrome...