Research Projects

Alzheimer's disease (AD) is the most common form of age-related dementia. This neurodegenerative disorder is characterized by massive neuronal death and deposition of amyloid-β peptide (Aβ), which is formed by processing of amyloid precursor protein (APP). The mechanism of neuronal degeneration in AD are not well understood, but growing evidence...

'A major portion of the eukaryotic genome is occupied by DNA sequences whose transcripts do not code for proteins. This part of the genome is transcribed in a developmentally regulated manner and in response to external stimuli to produce large numbers of long non-coding RNAs (lncRNAs). From the beginning of transcription through splicing and...

The aim of this Project is to create an International and Intersectoral network to facilitate the exchange of staff to progress developments in reminding technologies for persons with dementia which can be deployed in smart environments. The focus will be on developing staff and partner skills in the areas of user centered design and behavioral...

As Europe’s population is ageing, long-term care for elderly citizens will become an increasing cost for society. To manage this transition healthcare policy in the EU and individual Member States are heavily focused on extending the independent life of the elderly, with the dual aim of increasing their quality of life and reducing the costs of...

Age-related neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD), are a major public health problem since there is no effective treatment due to the poor understanding of the pathological processes involved in neuronal death. RNA editing, particularly A-to-I changes mediated by ADAR enzymes...

The pathogenesis of Alzheimer´s disease (AD) is not fully understood and no cure is available so far. Current therapeutic targets are insufficient and there is an urgent need for finding new pathways and mechanisms and novel targets to treat this terrible disease. Due to critical species-specific differences and the limitations of rodent models of...

Smart Health is EU Strategic Value Chain that contributes to growth, jobs and competitiveness. Health Data is the main enabler for the value chain, but it also depends on cutting edge technologies - AI, cloud computing, IoT, to integrate the dispersed knowledge and support innovative healthcare solutions and services. EC sets the creation of a...