Research Projects

This database contains information on EU funded dementia research projects, undertaken since 2007. It is the product of a mapping exercise of European funding programmes for dementia research conducted by Alzheimer Europe in 2020. This database is not an exhaustive resource of information. It contains information about dementia research projects that are funded by European programmes including FP7, H2020, IMI, JPND, AAL and the third EU Health programme. The mapping exercise and database were expanded in 2025, to include projects funded under Horizon Europe (including IHI). For these projects, the database reports the maximum contribution from the European Commission rather than the total project budget, so funding figures may not be directly comparable across all entries.
For an overview of projects, Alzheimer Europe is involved in, visit: https://www.alzheimer-europe.org/our-work/current-work

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Joint Action on Dementia 2015-2018

Joint Action on Dementia 2015-2018. The Joint Action will focus on two phases on work: approximately 12 months on developing a consensus on the best evidence of effective action in 4 key areas (diagnosis and post-diagnostic support; crisis and care coordination; quality of care in residential care settings; and dementia-friendly communities); and...

Funding Programme
EU health
Start Date
End Date
Total Funding
€ 1 498 710

Managing active and healthy aging with use of caring service robots

MARIO

MARIO addresses the difficult challenges of loneliness, isolation and dementia in older persons through innovative and multi-faceted inventions delivered by service robots. The effects of these conditions are severe and life-limiting. They burden individuals and societal support systems. Human intervention is costly but the severity can be...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 3 994 857
European Countries Involved

MiCrovasculaR rarefaction in vascUlar Cognitive Impairement and heArt faiLure

CRUCIAL

Vascular dementia and heart failure represent major health burden to morbidity, mortality and quality of life. Comorbidities (hypertension, aging, diabetes, etc.) affect all organs, but the brain and heart are especially sensitive to these chronic stresses resulting in cognitive impairment (a mental disorder) and heart failure (a non-mental...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 6 000 000
European Countries Involved

NANOPARTICLES FOR THERAPY AND DIAGNOSIS OF ALZHEIMER DISEASE

NAD

The search for effective therapies and early detection strategies for Alzheimer’s Disease (AD), the major cause of dementia in Europe, is imperative. It is known that β-amyloid (Aβ) peptide plays a central role in neurodegeneration. In AD brain, Aβ is released in a soluble form that progressively becomes insoluble forming aggregates; extracellular...

Funding Programme
EU-FP7
Start Date
End Date
Total Funding
€ 14 365 090

Nose-to-Brain Delivery of Biopharmaceutics for the therapy of central nervous system diseases: A design-based approach for efficient drug delivery systems

Bio2Brain

Bio2Brain aims to create a trans-European network of industrially oriented specialists fully trained and experienced, a significant driving force in innovating novel technologies to deliver biopharmaceuticals safely and via the nasal route of administration to the central nervous system (CNS). Diseases of the CNS and the spinal cord affect around...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 3 497 298
European Countries Involved

Peptide-Toxins as probes for the Structure –Activity Relationship (SAR) investigation against the nicotinic acetylcholine receptors (nAChRs) subtypes

PETOXSAR

This reintegration project will give to the applicant the opportunity to use the additional insights and expertise that he has gained during his previous MC-IEF to build on his experience for an independent academic career. The aim of this project is to investigate the structure - activity relationship (SAR) of synthesized peptides that selectively...

Funding Programme
EU-FP7
Start Date
End Date
Total Funding
€ 45 000
European Countries Involved

Preclinical in vivo proof-of-concept for cyclic oligopeptide rescuers of pathogenic protein misfolding and aggregation associated with neurodegeneration

PoC4ProMis

Within the ERC Consolidator Grant ProMiDis, my team and I have developed genetically engineered bacteria that function as a stand-alone, living discovery platform for short, drug-like cyclic peptides rescuing the misfolding and aggregation of proteins associated with human diseases (protein misfolding diseases, PMDs). By applying this technology...

Funding Programme
EU-Horizon Europe
Start Date
End Date
Total Funding
€ 150 000
European Countries Involved

PREDICTION OF ALZHEIMER’S DISEASE USING AN AI DRIVEN SCREENING PLATFORM

PREDICTOM

Alzheimer’s disease (AD) and related disorders leading to dementia are associated with staggering costs and suffering. Recently, there has been some progress in the search for effective therapeutic interventions and it is clear that any treatment is likely to be most effective if administered at the earliest stage of disease, but the health care...

Funding Programme
IHI
Start Date
End Date
Total Funding
€ 8 449 326

Prediction of cognitive properties of new drug candidates for neurodegenerative diseases in the early clinical development

PHARMA-COG

PHARMA-COG aims to develop a new integrated model to accelerate the development of drug candidates for MS, PKD and AD. The innovation relies on a 'multidimensional matrix' approach, integrating all available and renewed inputs (biomarkers/animal, human models/physiological and pharmacological challenges, Phase 0/1/1b to reduce the attrition rate...

Funding Programme
IMI
Start Date
End Date
Total Funding
€ 30 499 556

Prediction, Monitoring and Personalized Recommendations for Prevention and Relief of Dementia and Frailty

COMFORTAGE

COMFORTAGE is a joint effort of medical experts (i.e., neurologists, psychiatrists, neuropsychologists, nurses, memory clinics), social scientists and humanists, technical experts (i.e., data scientists, AI experts, robotic experts) and Digital Innovation Hubs to establish a pan European framework for Community-based, Integrated and People-Centric...

Funding Programme
EU-Horizon Europe
Start Date
End Date
Total Funding
€ 17 591 490

Remote Assessment of Disease and Relapse – Alzheimer’s Disease

RADAR-AD

There is an urgent need for novel approaches assessing functional decline in early AD. The main goal of the RADAR-AD project is to develop a digital platform to detect subtle functional deficits in early Alzheimer’s disease (AD) individuals by integrating a meaningful combination of smartphone, wearable and/or home sensor based parameters. The...

Funding Programme
IMI
Start Date
End Date
Total Funding
€ 7 640 145

Robotic Assistant for MCI patients at home

RAMCIP

RAMCIP will research and develop a novel domestic service robot, with the aim to proactively and discreetly assist older persons, MCI and AD patients in their every day life. Instead of simply being an obedient servant, the RAMCIP robot will have high-level cognitive functions, driven through advanced human activity and home environment modelling...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 3 981 178
European Countries Involved
 
Acknowledgement
Alzheimer Europe's database on research projects was developed as part of the 2020 Work Plan which received funding under an operating grant from the European Union’s Health Programme (2014–2020).