On 4 March, an international team of researchers from US and UK published a study in the PLOS One journal, reporting the association between dementia risk and combinations of frequently used drugs for dyslipidemia and hypertension.
The research team investigated data from 694,672 beneficiaries from the US- funded health insurance company, Medicare. The beneficiaries were all at least 67 years old and used both statins and antihypertensive drugs. Findings showed that specific combinations of statins and antihypertensive drugs may reduce risk for Alzheimer’s disease and related dementia (ADRD). The authors reported that two statins in particular, pravastatin and rosuvastatin, combined with angiotensin II receptor blockers (ARBs) or angiotensin converting enzyme (ACE) inhibitors were associated with reduced risk of ADRD. The risk was lower for people using pravastatin and rosuvastatin in combination with ARBs and the risk reduction was more apparent in men than in women.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229541
