On 18 November, researchers from the international public-private ROADMAP project published a new research paper in the journal of Alzheimer’s Research & Therapy.
The paper focusses on getting reliable estimates of health-related quality of life (HR-QoL) for people in different stages of Alzheimer’s disease, respectively who have mild cognitive impairment (MCI) or dementia.
In order to do so, the scientists systemetically searched for studies that reported on HR-QoL in these conditions. The team was able to include 61 studies after the application of their pre-defined ex- and inclusion criteria.
Reporting their results, the team notes that 48 of the studies used the EQ-5D for people with MCI or dementia and that 36 studies reported HR-QoL for mild and/or moderate disease severities. In addition to that, 12 studies reported utility values for MCI.
Concluding, the paper notes that there now exists substantial literature in this area, but reckons that further research is needed better understand HR-QoL in the earlier stages such as in people with preclinical and prodromal AD and MCI.
