The Real Word Dementia Outcomes (READ-OUT) study has recruited its first participants at Warneford Hospital in Oxford. This UK-wide study, led by Dementias Platform UK (DPUK), based at the University of Oxford and University of Cambridge, aims to recruit over 3,000 participants from 28 memory clinics and mobile community testing units across the UK. READ-OUT will access blood tests for detecting different types of dementia, such as Alzheimer’s disease, vascular dementia, frontotemporal dementia and dementia with Lewy bodies. The study will also explore whether these blood tests can detect dementia at various stages of the disease and if the results need to be adjusted in people from different ethnic backgrounds or with other health conditions like kidney disease. This research is part of the Blood Biomarker Challenge, a multi-million-pound programme supported by Alzheimer’s Society, Alzheimer’s Research UK, National Institute for Health and Care Research, Gates Ventures and players of People’s Postcode Lottery. The aim of the programme is to generate the evidence needed for dementia blood tests to be validated for use in the National Health Service (NHS) within the next 5 years.