LETHE project consortium meeting highlights innovative solutions for cognitive decline prevention

05/06/2023

On June 5th and 6th, the LETHE project, a European initiative aiming to develop and test a multidomain intervention program for the prevention of cognitive decline in older adults, held its consortium meeting in Bologna, Italy. The meeting provided an opportunity for the partners to share the main results achieved so far, the progress of work, and the plan for the next 12 months of project activities. Among the key topics discussed during the meeting, the following stood out:

1. The design of the LETHE Robot and Audio Glasses Sub-studies, which will kick off at the end of the year. The aim is to test new interaction technologies with the target population, namely the Temi robot and BOSE audio glasses, to perform the LETHE protocol. These technologies are expected to enhance the user experience and engagement with the intervention program, as well as provide personalized feedback and support.

2. An AI-driven risk stratification model that assesses the risk of cognitive decline in older adults. This model enables the identification of individuals with a high risk of cognitive decline at the start of a multidomain intervention program. By utilizing explainable AI techniques, we can examine the practicality of generating personalized risk profiles that offer valuable insights into individual risk and protective factors at the participant level. This approach represents an initial stage towards implementing an AI-driven personalized pathway for multidomain interventions within LETHE.

The meeting also featured the presentation of a knowledge base. Its purpose is to leverage the knowledge graph, which significantly connects data similar to how humans perceive and understand knowledge. This effectively simplifies the ability to discover information from analysed data. The formalisation of "relations" between "entities" through graphs allows data scientists to conduct entity analysis, link analysis, network analysis, and statistical analysis.

• Additionally, the meeting showcased the first release of the Brain Health literacy Portal and the Multilanguage video generation solution. These include a web and mobile accessible portal and a content generation tool, aimed at engaging end users and increasing health literacy regarding the main risk factors impacting cognitive decline. The portal will provide evidence-based information and recommendations on how to maintain a healthy brain, while the video generation solution will allow users to create multilingual videos on brain health topics using text-to-speech and speech-to-text technologies.

Dr. Sten Hanke, the LETHE project coordinator from FH Joanneum University for Applied Sciences, expressed his satisfaction with the outcomes of the meeting and thanked all the partners for their contributions. He also stressed the importance of continuing to work together towards the common goal of preventing cognitive decline and promoting healthy aging in Europe. The LETHE project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement no 101017405. Stay updated, subscribe to our newsletter: Join the LETHE community