The AMYPAD consortium, in its partnership with Aridhia and ADDI, is delighted to announce the external data release of its Prognostic and Natural History Study (PNHS). The study was established to collect amyloid PET scans in a large-scale population and included participants from 11 European parent cohorts of similar characteristics in a predementia phase. The integrated dataset represents the largest European PET dataset phenotyping longitudinally individuals at risk of Alzheimer’s disease (AD)-related progression. The public dataset has been incorporated into the AD Workbench of the Alzheimer’s Disease Data Initiative (ADDI), which is an open, global and free cloud-based platform for scientists to accelerate discoveries and innovations for AD and related dementias.
To access the data, you will need to make an online request via the AD Workbench. The current dataset includes a total of 3,368 participants. Of them, 1,620 underwent a baseline amyloid PET that includes the visual read and the Centiloid quantification (1,476 subjects), among other metrics. The participant’s clinical outcomes (e.g., cognition), disease (imaging) biomarkers, risk factors (e.g., genetics and environmental), and other relevant variables are included in the dataset. The dataset is planned to be further expanded, both in terms of parent cohorts and in available data (e.g. quantification of advanced MRI sequences, genetics, blood biomarkers, etc.). For more information about the dataset and how to access to the date, visit the project’s website:
https://amypad.eu/news/recent-news/data-from-amypad-pnhs-is-now-available-on-the-ad-workbench/