Research Projects

This database contains information on EU funded dementia research projects, undertaken since 2007. It is the product of a mapping exercise of European funding programmes for dementia research conducted by Alzheimer Europe in 2020. This database is not an exhaustive resource of information. It contains information about dementia research projects that are funded by European programmes including FP7, H2020, IMI, JPND, AAL and the third EU Health programme. The mapping exercise and database were expanded in 2025, to include projects funded under Horizon Europe (including IHI). For these projects, the database reports the maximum contribution from the European Commission rather than the total project budget, so funding figures may not be directly comparable across all entries.
For an overview of projects, Alzheimer Europe is involved in, visit: https://www.alzheimer-europe.org/our-work/current-work

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How to best meet the needs of people with dementia with severe behavioural disturbances. Toward a respectful and cost-effective model

RECAGE

The RECAGE project will tackle one of the most challenging problem arising during the clinical course of dementia: the so-called Behavioural and Psychological Symptoms of Dementia (BPSD). The current state-of-the-art of the treatment of these symptoms is still unsatisfactory and there are many unmet needs in this area. The major objective of the...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 2 824 038
European Countries Involved

Identification and modulation of pathogenic Amyloid beta-peptide species

AMYLOID

The frequency of Alzheimer's disease (AD) will dramatically increase in the ageing western society during the next decades. Currently, about 18 million people suffer worldwide from AD. Since no cure is available, this devastating disorder represents one of the most challenging socio-economical problems of our future. As onset and progression of AD...

Funding Programme
EU-FP7
Start Date
End Date
Total Funding
€ 2 497 020
European Countries Involved

Identification and validation of human proteins that control tau seeding in cell-based and in vivo models

Tau Seeding

The microtubule-associated protein tau is the most commonly misfolded protein in neurodegenerative disorders including Alzheimer’s disease and other related tauopathies. These neurological illnesses are hypothesized to share a common mechanism of disease progression, where pathogenic aggregates or ‘seeds’ of the tau protein function as templates...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 171 461
European Countries Involved

Identification of personalized inflammatory profiles of aging and senescence which are modified specifically by risk factors of dementia modulating the predementia speed of symptomatic progression.

PREADAPT

Age represents by far the largest risk factor for dementia, including Alzheimer’s disease (AD) dementia. However, not every person will develop dementia during aging, indicating that age-related processes may not inescapably lead to dementia. The elucidation of the fundamental processes occurring in aging will likely offer new options to prevent or...

Funding Programme
JPND
Start Date
End Date
Total Funding
€ 2 400 000
European Countries Involved

Identifying and deciphering the mechanism of the cellular machinery responsible for disaggregation of intracellular prion-like Tau aggregates

REVERSING TAUOPATHY

Tauopathies are a group of neurodegenerative diseases, the most common of them being Alzheimer’s disease, which are associated with the aggregation of protein Tau in the brain. Despite major research efforts world-wide, the mechanism of Tau aggregation and its pathogenesis giving rise to such neurodegenerative diseases is not yet understood...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 171 461
European Countries Involved

Identifying and treating SORL1-associated Alzheimer’s disease

SORLA-FIX

The majority of the risk to develop Alzheimer's disease is influenced by genetic factors. We previously found that carrying a genetic mutation in the SORL1 gene can lead to a greatly increased chance of developing Alzheimer's Disease. SORL1 is involved in the production and processing of Alzheimer proteins that accumulate in the brain. e have...

Funding Programme
JPND
Start Date
End Date
European Countries Involved

Immunological mechanisms of post-stroke dysfunction and recovery of neurovascular coupling

VasoRecovery

Ischemic stroke is one of the most common causes of disability and death in the EU. Improvements in treatment and prevention of ischemic stroke have reduced this burden, but consequently, patients living with chronic post-stroke conditions are increasing in number. Addressing this emergent public health problem will require novel rehabilitation...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 162 806
European Countries Involved

implementAtion anD OPeration of the gateway for healTh into BBMRI-ERIC

ADOPT BBMRI-ERIC

BBMRI-ERIC: the Biobanking and BioMolecular resources Research Infrastructure - European Research Infrastructure Consortium, aims to establish, operate and develop a Pan-European distributed research infrastructure in order to facilitate the access to biological resources as well as facilities and to support high quality biomolecular and biomedical...

Funding Programme
EU-H2020
Start Date
End Date
Total Funding
€ 4 949 449

IMplementation of quality indicators in PAlliative Care sTudy

IMPACT

New knowledge is not necessarily readily applied in medicine, even when there is evidence of its effectiveness. As a result of the gap between knowing and doing, policy makers, professional care providers, patients and their families have benefited too little from new developments. Implementation research has developed models for stepwise...

Funding Programme
EU-FP7
Start Date
End Date
Total Funding
€ 3 903 020
European Countries Involved

Improving health services for European citizens with dementia: Development of best practice strategies for the transition from ambulatory to institutional long-term care facilities

RIGHTTIMEPLACECARE

Given the increasing number of patients/consumers with dementia, political action is urgently required to prepare the health care services throughout Europe to deliver cost effective high quality long-term care to people concerned. Currently there is a lack of clinical research data of patients/consumers and informal caregivers to develop best...

Funding Programme
EU-FP7
Start Date
End Date
Total Funding
€ 3 897 650
European Countries Involved

Inflammation and AD: modulating microglia function focussing on TREM2 and CD33

PHAGO

Alzheimer’s disease (AD) is an age-related chronic neurodegenerative disease with four main pathological changes in the brain: amyloid plaques, fibrillary tau tangles, inflammation and neuronal loss. Phagocytes around amyloid plaques in late onset AD (LOAD) may be neurotoxic but have limited motility and phagocytic activity, suggesting a...

Funding Programme
IMI
Start Date
End Date
Total Funding
€ 18 088 176

Infrastructure-based EGNOS/Galileo receiver for personal mobility

IEGLO

The main goal of the proposed project IEGLO is the development of a handheld tracking device for elderly or Alzheimer disease people. At present, in Europe approximately 4.000.000 people are Alzheimer disease-ridden. Especially this people get very often in situations where they are un-oriented. They need mentoring by either their family members or...

Funding Programme
EU-FP7
Start Date
End Date
Total Funding
€ 387 327
European Countries Involved
 
Acknowledgement
Alzheimer Europe's database on research projects was developed as part of the 2020 Work Plan which received funding under an operating grant from the European Union’s Health Programme (2014–2020).