Research Projects

The mammalian central nervous system is an intricate and fragile structure which on one hand is open to change in order to store information, but at the same time is vulnerable to damage from injury, pathogen invasion or neurodegenerative diseases (NDs). Microglia, representing the brain`s innate immune system, execute a number of physiological...

In DynICP, we propose to develop an advanced, portable prototype of a non-invasive intracranial dynamic pressure (dynamic ICP) diagnosing and monitoring device which can be used at hospitals, point of care as well as at home. This device will consist of a wearable head gear capable of precise positioning of two ultrasonic transducers, software and...

The European costs of dementia were estimated €177 billion and there is a growing gap between burden and budget. The debilitation associated with dementia makes it the most feared of conditions related to ageing . Modelling studies have estimated that if obesity rates dropped by 5%, dementia prevalence rates would be lower by 6% and a decline in...

The societal burden of brain disorders, such as multiple sclerosis (MS), Alzheimers and Parkinsons disease is enormous and is considered one of the worlds most important health challenges. They affect millions of people worldwide and the annual healthcare costs are high and are increasing with the aging population. There is an immediate need to...

Under PhytoAPP project it is expected to build new and enhance existing network of international and inter-sectoral cooperation in the form of joint research and innovation activities between the project Partners with multidisciplinary skills and complementary competences in nanomaterials, physics, engineering, green chemistry, biochemistry and...

Alzheimer's disease (AD) is the most common neurodegenerative disorder affecting about 20 million people worldwide. Although aging is considered to be the most important risk factor for Alzheimer's disease, growing evidence from epidemiological studies suggest that type-2 diabetes (T2DM) increases the risk factor of AD. While compelling evidence...

Biological cells consist of a myriad of interacting biomolecules that collectively arrange in stable structures. For example, molecules undergo phase separation to form so-called biomolecular condensates. We now know that malfunctioning condensates can cause diseases like Alzheimer’s, Parkinson’s, and cancer. Yet, we do not understand how...

ProACT targets Europe’s 50 million multimorbid patients to proactively self-manage and offset the EU’s annual €700billion cost of chronic disease management. ProACT aims at providing and evaluating an open application programming interface to integrate a variety of new and existing technologies to advance ‘home based’ integrated care (IC). Cloud...

The vision of IASIS is to turn the wave of data heading our way into actionable knowledge for decision makers. This will be achieved by integrating data from disparate sources, including genomics, electronic health records and bibliography, and applying advanced analytics methods to discover useful patterns. Big Data in healthcare is in its early...

Internet-based and micro technologies have changed the way we live. But elderly people receiving care have not always benefited from these developments. IntegrAAL uses technology to help improve care for older people. Older people are often cared for by many different people, known as a circle of care. This circle may include informal carers as...

There is an enormous and unmet medical need to find efficient methods of prevention, diagnosis and disease-modifying therapies for tauopathies, including Alzheimer’s disease. The common molecular denominator of tauopathies are pathological forms of tau protein. Tau pathology relates to conformational changes during oligomerization and assembly...

The eHealthMonitor project provides a platform that generates a Personal eHealth Knowledge Space (PeKS) as an aggregation of all knowledge sources (e.g., EHR and PHR) relevant for the provision of individualized personal eHealth services. This is realised by integrating service-oriented architecture, knowledge engineering, multiagent systems, and...