Research Projects

In the brain, cells called astrocytes are as abundant as neurons, but are much less understood. Over the recent years, we have begun to appreciate how closely astrocytes support the development and function of synapses, the proposed substrate of memory. One emerging function of astrocytes is their direct involvement in learning and long-term memory...

Second to Alzheimer’s disease (AD) in prevalence, frontotemporal dementia (FTD) is a neurodegenerative condition resulting from the progressive deterioration of the frontal and temporal lobes of the brain. Cognitive and behavioural impairments are the most early and prevalent characteristic of FTD. In numerous studies, these disturbances have been...

Founded in 2010, CarThera is a clinical stage company that develops first-in-class medical devices using therapeutic ultrasounds to treat severe brain disorders (Glioblastoma, Brain Metastasis, Alzheimer’s Disease). The company is developing the SonoCloud Device, an implant emitting Low Intensity Pulsed Ultrasound (LIPU) to temporarily open the...

The increase in average lifespan across the world has been accompanied by an unprecedented upsurge in the occurrence of dementia with high socio-economic costs. The development of personal health systems provides a means of dealing with such problems in a meaningful and sustainable manner, enabling persons with dementia to maintain independence and...

"The COVID-19 pandemic continues to have a globally disproportionate impact on the well-being of people living with dementia particularly those who are community-dwelling who have seen reduced access to healthcare and increased risk of loneliness, isolation, and depression. Consequently, the 'home' has become a vital space of care that remains...

Dementia constitutes a major burden on society, both in monetary costs and the suffering of patients and their relatives. It comprises a number of diseases including Alzheimer’s disease (AD) and vascular dementia (VaD). In recent years, imaging biomarkers have been developed including measures of brain morphology (MRI T1), vascular pathologies (MRI...

Based on scientific findings from University of Oxford, and combined with the latest neuroimaging technologies, Mind over Matter is developing a ground-breaking technological solution to ignite and support a global dementia prevention movement.The low-cost technology comprises three parts:1. A headband with a small number of novel...

With an aging population and >55 million dementia cases worldwide; treatments are more needed than ever. However, effective treatments are lacking, with solutions only stalling dementia progress and no real disease-modifying effect. ATI has developed AT-001, a new drug with the potential to stop and revert the disease, and to delay its onset. AT...

The main aim of DISTINCT will develop a premier quality multi-disciplinary, multi-professional and intersectorial education and training research framework for Europe aimed at improving technology and care for people with dementia and their carers, and to use coherent themes an.d interrelated ESRs within DISTINCT to provide the evidence to show how...

Smart textiles that provide a seamless command-oriented user interface and have capable of wireless communication, have become active research field in recent decades with interest of wearable and attractive platforms. Well-known mechanical requirements such as light weight, compactness, and flexibility, that smart components should be invisibly...

This project aims to help people with dementia engage in social contexts to improve psychosocial wellbeing. People who are affected by Alzheimer’s disease or other dementias often face cognitive, behavioural and psychosocial difficulties, including impairment and degeneration of memory and of perceptions of identity. In a social context, this can...

This fellowship will co-develop, implement and evaluate the I-Do service to increase the socio-cultural participation and empowerment of people living with mild to moderate stages of dementia (PLWD) through an interdisciplinary engaged research approach that combines service design and psychology with a co-design methodology. This user-friendly...