Research Projects

ArrestAD proposes a novel and visionary thinking resulting from the demonstration of the central role of a particular heparan sulfate species at the intracellular level in neurons and in circulating cells in the molecular pathology of Alzheimer’s disease (AD). AD is a societal challenge for which there is neither prevention nor possible cure...

ONCOVISION is a Spanish SME specialised in design, development, production and commercialisation of organ-dedicated PET systems. Our company submits the present business innovation project with the overall objectives of (1) marketing an innovative brain-dedicated PET system to early diagnosis of Alzheimer’s disease (AD) and other causes of...

Europeans are the largest alcohol consumers. Policymakers and clinicians are currently perplexed on how to reduce alcohol harms in drinkers, due to contradictory guidelines: abstention is proposed as the healthiest option by many health advocates, stating that there is no safe level of alcohol intake; but most nonrandomized studies found lower all...

FluiDx-AD aims to transform Alzheimer’s disease (AD) diagnosis and prepare the EU healthcare systems for the emergence of new AD therapies, with a 1st-in-class trio of In Vitro Diagnostics tests.FluiDx-AD tests detect a unique and proprietary suite of biomarkers in simple bodily fluids (saliva, plasma/blood), towards widespread, patient-empowering...

Approximately 4060% of the European population is at risk of developing hearing loss due to exposure to unsafe noise levels. The EDHI fellowship will develop a novel toolkit sensitive to the first signs of hearing loss appropriate for use as an early diagnostic. This objective will be achieved by (1) ideating innovative behavioural and...

The project will build an application to help informal caregivers of demented people (typically a spouse or an adult child) understand and aid their demented relatives and help them manage their new life situation.

Alzheimer´s disease (AD) is the most common form of dementia, with over 35 million people suffering from it worldwide, and it constitutes a personal and societal tragedy of immense proportions. Fifty years of intense research have revealed many key elements of the biology of this neurodegenerative disorder. However, our understanding of the...

The aim of the project is to utilise state-of-the-art in ICT in order to develop an integrated solution for the  self-management of dementia patients, and develop innovative tools to support this procedure. This  solution can be conceived as an integrated platform enabling distant monitoring of patient status and  facilitating personalised...

The environment is one of the most crucial determinants of health. The Global Burden of Disease report estimates an emerging impact in terms of disability and reducing the quality of life worldwide, particularly for the aging populations. One of the root causes of this decline is likely to derive from the interaction of socio-environmental risk...

Frontotemporal dementia (FTD) has a debilitating effect on patients and their caregivers and leads to substantial economic costs. 15-30% of patients have familial FTD caused by known pathogenetic mutations. For the other 70-85% of patients, termed sporadic FTD, diagnosis is slow (~3.6 years) with frequent misdiagnosis due to clinical, genetic and...

By means of three different technologies, visual stimulation of mirror neurons in Alzheimer patients, an interactive agenda or diary and a movement monitoring system, people with dementia will be able to improve or sustain their cognitive functions. By developing, integrating and testing these technologies in home-care and residential settings we...

Problem. Coronary heart disease (CHD) patients have a 45% higher risk of cognitive impairment and dementia. Currently, there is no effective therapy to prevent or cure those brain-related diseases. Recent studies showed that physical activity is associated with better cognitive functioning and a risk reduction of cognitive impairment and dementia...