This database contains information on EU funded dementia research projects, undertaken since 2007. It is the product of a mapping exercise of European funding programmes for dementia research conducted by Alzheimer Europe in 2020. This database is not an exhaustive resource of information. It contains information about European projects that are funded by European programmes including FP7, H2020, IMI, JNPD, AAL and EU Health.

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A European DNA bank for deciphering the missing heritability of Alzheimer’s disease

EADB

Understanding the genetics of Alzheimer's disease (AD) is one of the best ways of improving our knowledge of the disease's underlying pathophysiological processes. Indeed, genetic factors account for up to 70% of the attributable risk in common forms of AD. The advent of genomic approaches has led to the characterization of 26 genetic determinants...

Funding Programme
Start Date
End Date
Total Funding
€ 3 644 713
European Countries Involved

A European multicentre double-blind placebo-controlled phase III trial of nilvadIpine in mild to moderate Alzheimer’s disease

NILVAD

Alzheimer’s disease (AD) is an ever-increasing public health concern among the aging population and is the most common form of dementia affecting more than 15 million individuals worldwide and around 5 million Europeans. The direct and indirect costs of AD and other dementias amount to more than €440,000 million each year (www.alz.org, 2010).Even...

Funding Programme
Start Date
End Date
Total Funding
€ 7 916 016

A HOME-based Spousal caregiver-delivered music Intervention for people living with DEmentia: A Randomised Controlled Trial

HOMESIDE

Our project aims to address the need for improved informal care by training cohabitating spouse caregivers to implement music interventions that target behavioural and psychological symptoms of dementia, and the quality of life and wellbeing of people with dementia, and of family caregivers. Our international randomised controlled trial involving...
Funding Programme
Start Date
End Date
Total Funding
€ 2 400 000
European Countries Involved

A strategy to investigate cell type-specific effects of non-coding regulatory elements to be applied in neurodegeneration research

NOJUNKDNA

I here propose a strategy to investigate cell type-specific effects of non-coding regulatory elements, which have been shown to play a fundamental role during the molecular pathophysiology of complex neurodegenerative diseases such as glaucoma in the eye or Alzheimer's or Parkinson's in the brain. By leveraging techniques from various scientific...
Funding Programme
Start Date
End Date
Total Funding
€ 171 461
European Countries Involved

A technology pLatform for the Assisted living of Dementia elDerly INdividuals and their carers

ALLADIN

The aim of the project is to utilise state-of-the-art in ICT in order to develop an integrated solution for the  self-management of dementia patients, and develop innovative tools to support this procedure. This  solution can be conceived as an integrated platform enabling distant monitoring of patient status and  facilitating personalised...
Funding Programme
Start Date
End Date
Total Funding
€ 1 980 757
European Countries Involved

A Treatment-Oriented Research Project of NCL Disorders as a Major Cause of Dementia in Childhood

DEM-CHILD

The DEM-CHILD project focusses on the main cause for childhood dementia in Europe, the neuronal ceroid lipofuscinoses (NCLs). The NCLs are neurodegenerative diseases characterized by dementia, blindness, epilepsy and physical decline leading to an early death of the patients. Since no cure is currently available, these disorders represent a serious...

Funding Programme
Start Date
End Date
Total Funding
€ 3 971 420
European Countries Involved

ACces to Timely Formal Care

ACTIFcare

In the absence of a cure for dementia, most research is aimed at an early diagnosis as it opens the way to timely future care and treatment, and can help people take control of their lives and plan ahead. However, people with moderate to severe dementia and their carers are often not receiving services of the type, quality and timing that they need...
Funding Programme
Start Date
End Date
Total Funding
€ 2 396 428
European Countries Involved

Advancing the non-invasive assessment of brain communication in neurological disease

TrueBrainConnect

Pathological communication between different brain regions has been implicated in various neurological disorders. However, the computational tools for assessing such communication from neuroimaging data are not sufficiently developed. The goal of TrueBrainConnect is to establish brain connectivity analysis using non-invasive electrophysiology as a...
Funding Programme
Start Date
End Date
Total Funding
€ 1 499 875
European Countries Involved

Aetionomy – Organising Mechanistic Knowledge about Neurodegenerative Diseases for the Improvement of Drug Development and Therapy

AETIONOMY

IMI’s Call 8 is geared to develop knowledge frameworks for ‘druggable mechanisms’ for two domains of pathophysiology. In response to this call, we propose (I) the development of a generic AETIONOMY pipeline to capture and infer over mechanistic knowledge of pathophysiology, and  (II) the focused application of this pipeline to derive clinically...

Funding Programme
Start Date
End Date
Total Funding
€ 17 546 060

affecTive basEd iNtegrateD carE for betteR Quality of Life

TeNDER

With an increasingly growing population in Europe, cognitive impairments as well as heart diseases are a major social and health issue. 1.2 million people in Europe are affected by Parkinson's disease (PD) while Alzheimer’s disease remains one of the biggest global public health challenges our generation is facing, while Cardiovascular disease...
Funding Programme
Start Date
End Date
Total Funding
€ 5 698 333
European Countries Involved

Altered mRNA translation as a pathogenic mechanism across neurodegenerative diseases

TRANSNEURO

Neurodegenerative and neurodevelopmental diseases constitute a major health burden, and in spite of several decades of intensive research, the molecular mechanisms underlying these diseases are still poorly understood, and effective drug treatments are generally lacking. Alterations in protein synthesis have been implicated in several of these...
Funding Programme
Start Date
End Date
Total Funding
€ 1 830 000
European Countries Involved

Alzheimer Disease - gut connection

AD-gut

Alzheimer’s disease (AD) is the leading cause of dementia in the Western world and to date no cure nor any preventive strategy are available for this neurodegenerative disorder. Bacterial 16S rRNA sequencing from fecal samples revealed a remarkable shift in the gut microbiota of conventionally-raised AD mice compared to healthy, wild-type mice...
Funding Programme
Start Date
End Date
Total Funding
€ 7 686 620
European Countries Involved
 
Acknowledgement
Alzheimer Europe's database on research projects was developed as part of the 2020 Work Plan which received funding under an operating grant from the European Union’s Health Programme (2014–2020).