Research Projects

This database contains information on EU funded dementia research projects, undertaken since 2007. It is the product of a mapping exercise of European funding programmes for dementia research conducted by Alzheimer Europe in 2020. This database is not an exhaustive resource of information. It contains information about European projects that are funded by European programmes including FP7, H2020, IMI, JNPD, AAL and EU Health.

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3-O-sulfated heparan sulfate translocation in altered membrane biology: A new strategy for early population screening and halting Alzheimer’s neurodegeneration

ArrestAD

ArrestAD proposes a novel and visionary thinking resulting from the demonstration of the central role of a particular heparan sulfate species at the intracellular level in neurons and in circulating cells in the molecular pathology of Alzheimer’s disease (AD). AD is a societal challenge for which there is neither prevention nor possible cure...
Funding Programme
Start Date
End Date
Total Funding
€ 3 991 096
European Countries Involved

A European DNA bank for deciphering the missing heritability of Alzheimer’s disease

EADB

Understanding the genetics of Alzheimer's disease (AD) is one of the best ways of improving our knowledge of the disease's underlying pathophysiological processes. Indeed, genetic factors account for up to 70% of the attributable risk in common forms of AD. The advent of genomic approaches has led to the characterization of 26 genetic determinants...

Funding Programme
Start Date
End Date
Total Funding
€ 3 644 713
European Countries Involved

A European multicentre double-blind placebo-controlled phase III trial of nilvadIpine in mild to moderate Alzheimer’s disease

NILVAD

Alzheimer’s disease (AD) is an ever-increasing public health concern among the aging population and is the most common form of dementia affecting more than 15 million individuals worldwide and around 5 million Europeans. The direct and indirect costs of AD and other dementias amount to more than €440,000 million each year (www.alz.org, 2010).Even...
Funding Programme
Start Date
End Date
Total Funding
€ 7 916 016

ACces to Timely Formal Care

ACTIFcare

In the absence of a cure for dementia, most research is aimed at an early diagnosis as it opens the way to timely future care and treatment, and can help people take control of their lives and plan ahead. However, people with moderate to severe dementia and their carers are often not receiving services of the type, quality and timing that they need...
Funding Programme
Start Date
End Date
Total Funding
€ 2 396 428
European Countries Involved

Active Living For Alzheimer-patients -ALFA

ALPHA

By means of three different technologies, visual stimulation of mirror neurons in Alzheimer patients, an interactive agenda or diary and a movement monitoring system, people with dementia will be able to improve or sustain their cognitive functions. By developing, integrating and testing these technologies in home-care and residential settings we...
Funding Programme
Start Date
End Date
Total Funding
€ 2 162 987
European Countries Involved

Adaptive Implementation and Validation of the positively evaluated Meeting Centers Support Programme for people with dementia and their carers in Europe

MEETINGDEM

MEETINGDEM aims to implement and evaluate the innovative Meeting Centres Support Programme (MCSP) for community dwelling people with dementia and their family carers, in three European countries: Italy, Poland and the United Kingdom. This person-centred approach has been positively evaluated and adaptively implemented in 118 meeting centres in the...
Funding Programme
Start Date
End Date
Total Funding
€ 1 199 819
European Countries Involved

Aetionomy – Organising Mechanistic Knowledge about Neurodegenerative Diseases for the Improvement of Drug Development and Therapy

AETIONOMY

IMI’s Call 8 is geared to develop knowledge frameworks for ‘druggable mechanisms’ for two domains of pathophysiology. In response to this call, we propose (I) the development of a generic AETIONOMY pipeline to capture and infer over mechanistic knowledge of pathophysiology, and  (II) the focused application of this pipeline to derive clinically...

Funding Programme
Start Date
End Date
Total Funding
€ 17 546 060

Altered mRNA translation as a pathogenic mechanism across neurodegenerative diseases

TRANSNEURO

Neurodegenerative and neurodevelopmental diseases constitute a major health burden, and in spite of several decades of intensive research, the molecular mechanisms underlying these diseases are still poorly understood, and effective drug treatments are generally lacking. Alterations in protein synthesis have been implicated in several of these...
Funding Programme
Start Date
End Date
Total Funding
€ 1 830 000
European Countries Involved

Alzheimer's disease apolipoprotein pathology for treatment elucidation and development

ADAPTED

Alzheimer’s disease (AD) affects over 35 million people worldwide and yet there are currently no medicines which slow down the progress of the disease. The ADAPTED project aims to boost the development of new medicines by investigating an area of AD research which has previously received little attention – the APOE gene. The APOE gene is a well...
Funding Programme
Start Date
End Date
Total Funding
€ 6 796 740
European Countries Involved

Alzheimer’s disease data-driven insights on individual outcomes of importance

ADDITION

Alzheimer’s disease (AD) is the most common cause of dementia in the elderly, and a major reason for disability and death. The time course of AD varies between different people affected, and being able to tell in advance how the disease is likely to progress would have a great value for patient, their caregivers and for all of society. In the...
Funding Programme
Start Date
End Date
Total Funding
€ 1 100 000
European Countries Involved
 
Acknowledgement
Alzheimer Europe's database on research projects was developed as part of the 2020 Work Plan which received funding under an operating grant from the European Union’s Health Programme (2014–2020).