Research Projects

Dementia is a group of disorders characterized by severe memory loss ultimately impairing daily life activities. Major forms are Alzheimer’s disease, Lewy body dementia, and frontotemporal dementia. Each dementia type is caused by different biological factors and therefore requires a specific treatment targeting these factors. To develop effective...

The main aim of DISTINCT will develop a premier quality multi-disciplinary, multi-professional and intersectorial education and training research framework for Europe aimed at improving technology and care for people with dementia and their carers, and to use coherent themes an.d interrelated ESRs within DISTINCT to provide the evidence to show how...

Neurodegenerative disorders such as, Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), stroke, Traumatic Brain Injury (TBI) and chronic stress create a major economic burden to society and a substantial reduction in quality of life for patients and families. The development of neuroregenerative therapies is notoriously difficult and...

Alzheimer’s disease (AD) is a devastating disorder without a cure. Recent research demonstrates a link between AD and exposure to high levels of air pollution, yet detailed understanding of the connection does not exist. Air pollution, a massive public health issue known to pose a major threat to humans, is an increasing global concern. Researchers...

The majority of the risk to develop Alzheimer's disease is influenced by genetic factors. We previously found that carrying a genetic mutation in the SORL1 gene can lead to a greatly increased chance of developing Alzheimer's Disease. SORL1 is involved in the production and processing of Alzheimer proteins that accumulate in the brain. e have...

BBMRI-ERIC: the Biobanking and BioMolecular resources Research Infrastructure - European Research Infrastructure Consortium, aims to establish, operate and develop a Pan-European distributed research infrastructure in order to facilitate the access to biological resources as well as facilities and to support high quality biomolecular and biomedical...

Dementia raises complex challenges for people with dementia, their families, and society. The European Parliament has called for investment in high quality, innovative technology research to improve dementia care but so far there has been little benefit because research has generally been limited, small scale and methodologically flawed. In...

The long-term goal of this project is to understand how neuronal assemblies exchange information (functional or neuronal communication), and how variability in neuronal communication explains variability in behavioural performance, both in the intact and injured brain. Communication involves temporal interactions between neuronal assemblies either...

MADIA aims at realizing a versatile and cheap diagnostic device based on magnetoresistive sensors, microfluidic device, ultra–small Magnetic Nanoparticles (MNPs) and advanced bio-chemical functionalization methods for the early and ultrasensitive. in vitro detection of biomarkers trustfully associated with 2 incurable neurodegenerative diseases...

Medical diagnosis is currently undergoing a major revolution due to the fast discovery of molecular biomarkers, and the development of multimodal “metabiomarker” signatures. Progress, however, is hindered by low abundance of many biomarkers of interest in body fluids, in absolute concentration and with regard to other biomolecules. The aim of the...

Bio2Brain aims to create a trans-European network of industrially oriented specialists fully trained and experienced, a significant driving force in innovating novel technologies to deliver biopharmaceuticals safely and via the nasal route of administration to the central nervous system (CNS). Diseases of the CNS and the spinal cord affect around...