There is, as yet, no cure available for dementia and Alzheimer disease (AD). With prevention therefore being identified as a global priority, the EU-FINGERS consortium aimed to work towards a novel multimodal precision prevention toolbox, based on an existing successful multimodal lifestyle/vascular prevention model, FINGER (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability) and on a precision prevention and early detection (PPED) approach, adapted from cancer research.
The EU-FINGERS Toolbox included the full range of tools needed to start the next generation of AD dementia prevention trials, within the framework of precision medicine. The aim was to deliver targeted and timely interventions to effectively prevent/delay dementia. The Toolbox also provided a common framework and aligned main European cohorts in the AD research field, to deliver results easily implementable in Europe.
The project aligned multinational cohorts from observational studies and recent landmark multimodal dementia prevention trials, with new unique long-term trial data. The entire continuum from at-risk and preclinical to prodromal disease stages was covered, with deep comprehensive clinical, functional and biological assessments.
EU-FINGERS (INTER/JPND/19/BM/14012609) was an EU Joint Programme - Neurodegenerative Disease Research (JPND) project and was supported by the Luxembourg national research fund (FNR).
