A growing body of evidence from epidemiological and animal studies shows that exposure to air pollutants can impair the brain. The ADAIR project therefore aims to provide crucial mechanistic insight about the effects of air pollutants on the brain in humans and discover biomarkers for air pollution and Alzheimer’s disease (AD) risk prediction.
ADAIR addresses a major societal challenge with wide health-related, environmental, economic, scientific, social, and political impact. Lowering the incidence of AD attributable to air pollution and contribution to the mitigation of climate change, are closely linked. The ultimate goal is to develop strategies for early identification of people at risk of AD, and to discover novel targets for preventive strategies in AD.