On 6 February, US researchers from the University of Mississippi Medical Center published a report examining the association between systemic inflammation measured during midlife and later cognitive decline in the journal Neurology. In the published study, scientists analysed five known inflammatory biomarkers in blood samples from a total of 12.336 people participating in the Atherosclerosis Risk in Communities Study (ARIC), which is a prospective epidemiologic study conducted in four US communities. The participants were then followed for approximatively 20 years. Cognitive assessments (memory, executive function and language) were evaluated over three visits at the beginning, six to nine years later and at the end of the study. They found that people with high levels of inflammatory markers measured in midlife had stepper cognitive decline over the next 20 years compared to those with low inflammatory biomarkers.
http://n.neurology.org/content/early/2019/02/13/WNL.0000000000007094
