On 28 January, French and German researchers published a research paper analysing the potential association between the use of antiepileptic drug and the dementia risk in the journal of Alzheimer’s disease. In the published report, scientists performed a case-control study using data from the Disease Analyzer database. They analysed data from 101.150 individuals followed by general practitioners and neuropsychiatrists in Germany between 2013 and 2017. The study population included 50.575 people with dementia and 50.575 controls without dementia with a mean age of 81 years old. Overall, they described no significant association between antiepileptic drug use and dementia risk. However, levetiracetam generic drugs were found to be associated with an increased dementia risk. Researchers also pointed out several limitations of the study and recommended further analysis.
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad181194