The Project Coordinator is the intermediary between the Innovative Medicine Initiative Joint Undertaking (IMI-JU) and the consortium in all scientific and industry related concerns. The Managing Entity is the second intermediary between the IMI-JU and the Consortium and is concerned with contractual and funding related matters concerning the participating academic institutions and SMEs. Each Work Package has a leader and a co-leader from academic institution or industry. They are jointly responsible for the milestones and deliverables of their WP and for engaging and communicating with all the partners in the project.