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WP7: Quantitative Pharmacology

Work Packages

Pharmacog Logo

Main Objectives

  • Define and standardise protocol for analytical measures across sites
  • Coordinate and conduct analysis of samples from all clinical and pre-clinical studies conducted
  • Define mathematical models to be utilised for optimising study design based on describing the relationship between
    • drug exposure and the pharmacological response measured
    • cognitive challenge and resultant cognitive deficit
    • predictive capacity of pre-clinical biomarkers and models for man
    • predictive capacity of clinical markers/models for modelling disease progression
    • predictive capacity of clinical markers/models for predicting eventual efficacy

WP Leads

Academic lead: Pr Gianluigi Forloni (MNI, Italy)

Industry lead: Dr Oscar DellaPasqua (GSK)

WP Partners

  • MarioNegri Institute, Italy
  • GSK
  • J&J
  • Lundbeck



Last Updated: Thursday 14 October 2010


  • Acknowledgements

    The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) for the Innovative Medicine Initiative under Grant Agreement No 115009.
  • Innovative Medicines Initiative
  • European Union
  • European Federation of Pharmaceutical Industries and Associations