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Science watch

 

Our science watch section reports on the story behind the media-reported “breakthrough” headlines in dementia, by focusing on the original journal study. Reports of other developments in research on care and cure are also included.

24/06/2020 Clinical study published in Neurology indicates that hormonal changes may contribute to the increased prevalence of Alzheimer’s disease in women
23/06/2020 Clinical study links obesity with dementia risk
22/06/2020 Study of post-mortem brain samples shows striking differences in Tau between individuals, contributing to clinical heterogeneity in AD
17/06/2020 AriBio announces the completion of enrolment of its Phase II trial with AR1001 for AD
17/06/2020 Pooled study analysis shows how combinations of lifestyle factors may affect Alzheimer’s disease risk
15/06/2020 Amylyx Pharmaceuticals announces completion of enrolment of its PEGASUS Phase II trial for Alzheimer’s disease
04/06/2020 Anavex Life Sciences receives regulatory approval to expand its Anavex 2-73 Phase II/III trial for AD in Canada and UK
29/05/2020 New study reports that nilotinib, an FDA-approved drug for leukaemia, is safe and well-tolerated in AD Phase II trial
28/05/2020 FDA approves flortaucipir PET tracer for AD diagnosis
28/05/2020 Neurotrope launches a new long-term clinical trial of Bryostatin-1 in Alzheimer’s disease
27/05/2020 University of Pittsburgh will use USD 2.6 million NIH award to examine how biological factors affect brain disease
20/05/2020 TauRx Therapeutics Ltd reports that hydromethylthionine could slow clinical decline and brain atrophy in behavioural variant Fronto-Temporal Dementia
19/05/2020 Meta-analysis reveals that reducing the blood pressure of older people with hypertension can reduce the risk of dementia
15/05/2020 Cassava Sciences announces that its Phase II clinical trial of PTI-125 in mild-to-moderate AD did not meet the primary endpoint
13/05/2020 Study in mice reveals that retinal imaging technology could detect an early warning sign of Alzheimer’s disease

 

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