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PRIME project hosts a webinar on the clinical aspects of neurodevelopmental disorders

Tuesday 30 March 2021

The EU-funded PRIME project is investigating whether disturbances in insulin signalling in the brain are linked to different neurodevelopmental and neurodegenerative disorders, using a wide range of scientific and clinical approaches. On 30 March, PRIME organised a webinar to inform project collaborators (including students, researchers and data scientists) about the clinical aspects of neurodevelopmental disorders, focusing on attention deficit and hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD) and autism spectrum disorder (ASD). 

During the webinar, Prof. Jan Buitelaar of Radboud University Medical Centre delivered a presentation that reviewed the clinical characteristics of these neurodevelopmental disorders, discussing their symptoms at onset, outlining how they develop over time and highlighting common treatments.  While they share certain similarities, including the early age for onset and genetic risk factors, there are also differences, such as the types of behaviour that are demonstrated by people living with ADHD, OCD or ASD. In PRIME, researchers are now working to unravel the biological mechanisms that might account for these similarities and differences, aiming to understand the contribution of insulin and how this relates to other brain disorders including Alzheimer's disease.