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PharmaCog researchers show progress at ECCN conference

Saturday 03 October 2015

The PharmaCog project was very well represented at ECCN, the 15th European Congress on Clinical Neuro­physiology that took place in Brno, Czech Rep. during 30 September - 3 October 2015.

Susanna Lopez presented the following papers:

  • “Auditory oddball event-related potentials cortical sources are related to cerebrospinal fluid (CSF) β Amyloid (Aβ) level in amnesic MCI subjects.”
  • “Abnormal delta cortical sources of resting state eyes closed EEG rhythms correlate with cerebrospinal fluid (CSF) β Amyloid (Aβ) level in amnesic MCI subjects.”
  • “EEG markers of motor activity in physiological aging and Alzheimer's disease mouse models.”

Claudio Babiloni presented:

  • "Of Mice and Men: impact of Alzheimer‘s disease on cortical generation of EEG rhythms in mice and humans towards a true translational mode.”
  • “Cortical Generation of On-going "Delta" and "Alpha" EEG Rhythms in Mouse Models of Alzheimer‘s disease and Alzheimer’s disease Patients at Prodromic and Manifest Stages.”

Wilhelmus Drinkenburg presented “Pharmacological Neuromodulation of on-going "Delta" and "Alpha" EEG Rhythms: Evidence for Translational Neurophysiological Biomarkers in Alzheimer‘s Disease Animal Models.”

The PharmaCog project is developing models to predict the efficacy of drug candidates by combining past and current data to define a series of biomarkers of dementia progression. The project aims to propose to the pharmaceutical industry and academic research laboratories new methods for successfully developing new drugs for the treatment of Alzheimer's disease.