The biggest group of diseases is made up of neurodegenerative diseases, which are characterised by a progressive loss of nerve cells and synapses.

For most of these diseases, the causes of this nerve loss are unknown and our knowledge about possible treatment or prevention remains limited.

• FAMILIAL ALZHEIMER DISEASE (FAD)
• DEMENTIA WITH LEWY BODIES (DLB)
• DEMENTIA IN PARKINSON’S DISEASE (PDD)
• FRONTO-TEMPORAL DEGENERATION (FTD)
  • CLINICAL MANIFESTATION
    • Fronto-temporal dementia (FTD)
    • Primary Progressive Aphasia (PPA)
    • Semantic Dementia (SD)
  • HISTOPATHOLOGICAL SUB-TYPES
    • FTD with parkinsonism linked to chromosome 17 (FTDP-17)
    • Pick’s disease (PiD)
    • Dementia lacking distinctive histology (DLDH)
• PROGRESSIVE SUPRANUCLEAR PALSY (PSP)
• CORTICOBASAL DEGENERATION (CBD)
• ARGYROPHILIC GRAIN DISEASE (AGD)
• MULTIPLE SYSTEM ATROPHY (MSA)
• AMYOTROPHIC LATERAL SCLEROSIS (ALS)
• ATAXIAS
• HUNTINGTON’S DISEASE (HD)
• DOWN SYNDROME
• FAMILIAL BRITISH DEMENTIA