Metabolic diseases are a group of often treatable diseases which may lead to dementia and which are caused by an under-activity or over-activity of a part of the human metabolism.

• THYROID DISORDERS
• NEURO-DEGENERATION WITH BRAIN IRON ACCUMULATION TYPE I (NBIA 1)
• CEREBRAL LIPIDOSES
  • TAY-SACHS DISEASE (TSD)
  • SANDHOFF DISEASE
  • GAUCHER DISEASE
  • NIEMANN-PICK DISEASE (NPD)
  • KRABBE DISEASE
  • NEURONAL CEROID LIPOFUSCINOSES (NCL)
  • CEREBROTENDINOUS XANTHOMATOSIS (CTX)
• DEMENTIA IN HEPATIC AND RENAL FAILURE
• DEMENTIA DUE TO CHRONIC HYPOVITAMINOSIS
• METACHROMATIC LEUKODYSTROPHY (MLD)
• ADRENOLEUKODYSTROPHY (ALD)