WP2: Development and validation of translatable provocation challenges (Pre-clinical studies)
- To develop validated pre-clinical challenge models with increased predictive capacity to support ranking of novel drugs.
- To further test the reproducibility and sensitivity of novel biomarkers that can be used for PK/PD studies.
- To establish mathematical models describing the relationship between drug exposure and biomarker response and the relationship between pre-clinical and clinical studies.
Academic Lead: Dr Fabienne Aujard (CNRS, France)
Industry Lead: Dr Yves Lamberty (UCB)
- University of Lille, France
- University of Murcia, Spain
- CNRS, France
- University of Verona, Italy
- University of Foggia, Italy
- Mario Negri Institute, Italy
Last Updated: lundi 18 octobre 2010